Medication Guide During Pregnancy

Pregnant women may safely take the following over-the-counter medications – following all the directions on the container for adult dosage/use. Generic substitutes are OK. If on other medications, consult your obstetrician before use.  It is safe for pregnant women to take Tylenol/ Acetaminophen when taken according to the package directions.

At any time during your pregnancy, it is NOT OK to consume

  • Alcohol
  • Beer
  • Wine
  • Marijuana
  • Street Drugs
  • Cigarettes
  • e-Cigarettes


  • Aspirin products
  • Advil
  • Aleve
  • Ibuprofen

If you have any further questions about a medication, be sure to ask your nurse or OB-GYN doctor.

Over-the-Counter Medications

ProblemOver-the-Counter MedicationsCall Your Obstetrician If You Have
Mild headaches/aches and painsTylenol (Acetaminophen) DO NOT exceed 3000mg/day
Extra Strength Tylenol (Acetaminophen) DO NOT exceed 3000mg/day
Severe and/or persistent headaches
Nasal congestion due to a cold, sinusitis, or allergiesAfrin Nasal Spray (for 3 days only)
Claritin plain,
NOT Claritin D
Neti Pot
Saline Nasal Spray
Sudafed (plain), after 1st trimester (13 weeks)--as long as not taking blood pressure medication
Cough due to a cold or minor throat irritationBenadryl (may cause drowsiness) — check with MD first if hyperthyroid, blood pressure, asthma, bladder problems, or ulcers
Robitussin DM (not to exceed 1 week of use)
Vicks VapoRub
Persistent cough
Sore throatAlcohol-free lozengesSevere or persistent sore throat
If above medications not effective, may try OTC Pepcid or Zantac as directed
No relief
Milk of Magnesia
Severe straining
Mild to moderate diarrheaImodium
No relief
GasGas-X (simethicone)
HemorrhoidsAnusol HC
Chilled witch hazel packs
Sitz bath
Bleeding or severe pain
InsomniaWarm bath
Warm milk
Vitamin B6 (50 mg)
Benadryl (check with MD, as above under “Cough due to a cold or minor throat irritation”)
Tylenol PM Unisom, 1 tablet at bedtime
Nausea (morning sickness)5 to 6 small meals per day
Vitamin B6 (10-25 mg three or four times a day)
Unisom 1⁄2 tablet 2 times daily or 1 tablet at bedtime
Persistent vomiting, weight loss, or inability to tolerate fluids for 24 hours
Yeast infectionsOTC 7-day Monistat (more effective than 1- or 3-day course)No relief – call for appointment to evaluate
AllergiesAfrin Nasal Spray (for 3 days only)
Benadryl (may cause drowsiness)
Sore musclesIcy Hot

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