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Medication Guide
During Pregnancy

Pregnant women may safely take the following over-the-counter medications – following all the directions on the container for adult dosage/use. Generic substitutes are OK. If on other medications, consult your obstetrician before use.  It is safe for pregnant women to take Tylenol/ Acetaminophen when taken according to the package directions.

At any time during your pregnancy, it is NOT OK to consume

  • Alcohol
  • Beer
  • Wine
  • Marijuana
  • Street Drugs
  • Cigarettes
  • e-Cigarettes


  • Aspirin products
  • Advil
  • Aleve
  • Ibuprofen

If you have any further questions about a medication, be sure to ask your nurse or OB-GYN doctor.


Problem Over-the-Counter Medications Call Your Obstetrician If You Have
Mild headaches/aches and pains Tylenol (Acetaminophen) 325 mg- DO NOT exceed 3000 mg a day
Extra Strength Tylenol (Acetaminophen) 500 mg -DO NOT exceed 3000mg a day
Severe and/or persistent headaches
Nasal congestion due to a cold, sinusitis, or allergies

Neti Pot
Afrin Nasal Spray (for 3 days only)
Saline Nasal Spray
Guaifenesin 600 mg as directed on package
Guaifenesin with Dextromethorphan
Phenylephrine, after 1st trimester (14 weeks 0 days and beyond)--as long as not taking blood pressure medication

 Not recommended in pregnancy unless approved by a doctor: pseudoephedrine

Cough due to a cold or minor throat irritation Robitussin plain
Robitussin DM (after first trimester)
Vicks VapoRub
Cough drops/Lozenges (sugar free if diabetic)
Persistent cough
Sore throat Alcohol-free lozenges Severe or persistent sore throat
Heartburn Tums
If above medications not effective, may try over the counter Pepcid as directed
No relief
Constipation Metamucil
Milk of Magnesia
Severe straining
Mild to moderate diarrhea Imodium
No relief
Gas Gas-X (simethicone)  
Hemorrhoids Anusol HC
Chilled witch hazel packs
Sitz bath
Preparation H
Bleeding or severe pain
Insomnia Warm bath
Warm milk
Vitamin B6 (50 mg)
Benadryl (25 mg)
Tylenol PM
Unisom, 1 tablet (25 mg) at bedtime
Nausea (morning sickness) 5 to 6 small meals per day
Peppermint Lifesavers or gum
Ginger tablets (250-500mg two to three times a day)
Vitamin B6 (10-25 mg three or four times a day) (up to 200 mg/day)
Unisom (with DOXYLAMINE as the active ingredient) 1⁄2 tablet (12.5mg) 2 times daily or 1 tablet (25mg) at bedtime
Persistent vomiting, weight loss, or inability to tolerate fluids for 24 hours
Yeast infections OTC 7-day Monistat (more effective than 1- or 3-day course) No relief – call for appointment to evaluate
Allergies Afrin Nasal Spray (for 3 days only)
Benadryl (may cause drowsiness) — check with MD first if hyperthyroid, blood pressure, asthma, bladder problems, or ulcers,
Claritin plain
Zyrtec plain
Sore muscles Icy Hot
Tylenol (Acetaminophen) 325mg
Extra Strength Tylenol (Acetaminophen) 500 mg
Heat pad


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